Monday, November 26, 2012

Citicoline: Supplement for the Brain?

      Citicoline is a novel nutrient with the potential to treat a variety of neurological dysfunctions.  It is already being prescribed by physicians in some countries to help treat such conditions.   Citicoline is well absorbed via oral and IV administration. It can also be obtained through a variety of fresh food sources.  Either way it crosses the blood brain barrier and is broken down into cytidine and choline.   Cytidine is necessary for the formation of nucleotides and both are required by the structural components of neuronal cellular membranes. 

     In the event of neuronal cellular damage, as would be the case in ischemic stroke or other type of brain injury, the release of certain chemicals such as free fatty acids, glycerol, and arachidonic acid occurs.   Additionally, toxic metabolites and free radicals are accumulated causing further damage to the brain.   Supplementation with citicoline can help sequester this process. The methods which are known to be implemented for this effect include promoting the synthesis of acetylcholine, phosphoplipids, and halting the free fatty acid accumulation that can lead to more extensive damage.  The phospholipids that are generated with the assistances of citicoline are required to maintain the structural integrity of the neuronal cell membranes.

     Studies have been conducted with mixed results regarding the benefits of citicoline on problems related to neurological dysfunctions.  Some small animal and human studies have found beneficial effects of the afore mentioned supplement on conditions like Alzheimer’s disease, learning and memory,eye and mental health as well as appetite control.   More studies need to be conducted to validate these results.  Recently, the largest clinical trial conducted on the effects of citicoline on stroke was completed.  Unfortunately the results were not promising as they proved that citicoline was not protective against the damage incurred following a stroke.  Overall it is known to be a safe supplement to take for a period of 90 days.   Safety of long term use has not been established.


Endres, Irfan, ND, and John R. Endres, ND. "Citicoline: A Novel Therapeutic Agent with Neuroprotective, Neuromodulatory, and Neuroregenerative Properties." Natural Medicine Journal 2.6 (2010): 11-24. Web.

Kamel, Hooman, MD. "Citicoline Disappoints as a Neuroprotectant After Ischemic Stroke." Online posting. Journal Watch. N.p., 17 July 2012. Web. 26 Nov. 2012. <>.

Laidlaw, Sarah H., MS. "Citicoline: A Promising Dietary Supplement for Preventing Cognitive Decline." Integrative RD 13 (2011): 32-34. Print

Tuesday, November 13, 2012

Part Two: My FNCE 2012 Experience

  Following the DIFM Pre-FNCE workshop, I attended the opening ceremony which included an address by keynote speak Mr. Dean Karnazes, an ultra marathon runner and successful businessman.  One of his claims to fame was a three day non stop run that he was able to accomplish because of a unique ability to metabolize lactic acid in such a way that he does not get fatigued.  Well, his story of perseverance and endurance was meant to inspire the nutrition professionals in attendance to take charge as they forge ahead in their careers.   I also attended two networking events while I was there.  The events were hosted by the Nutrition Entrepreneurs  DPG and Renal Dietitians DPG.   It was interesting to see what other dietitians around the country were up to and how they were going about enhancing their careers while having some fun.    

   Finally there were all the wonderful lectures I had the pleasure to attend.   Below I have outlined some of the major points that I felt were notable to mention of the things I managed to pick up while I was there:     


“Calling All Food Bloggers: Stay in the Game”

Toby Amidor

Dana Angelo White


--- 70% of households cook their meals at home.  
--- RD's should be food blogging
---- Tweet at least once a day
---- Put up your blogs/tweets early in the morning as most people
like to check their facebook/blogs early in the day. This will help
drive traffic to your site.
-- have a separate fan page on facebook for your blogs and
advertise your posts on that page versus your own page

“Forewarned if Forearmed: Legal Use of Social Media”

Debra King

Stephen Stromberg

--- Do not give personal diet advice on social media forums. Take
it off facebook and discuss in private. Even if they are friends!!
-- Do not plagiarize and make sure you give credit to your sources.

“The Dollars and Sense of Telehealth: Designing Programs to Maximize Effectiveness”

Mary Ann Hodorowicz, MBA, RD, LDN, CDE

Joanne Shearer, MS, RD, LN

--Telemedicine and telenutrition are gaining ground.
-- You can actually obtain reimbursement for online nutrition
counseling but you have must contact the individual insurance
companies. Some may only reimburse with the use of video
-- Make sure you contact whatever states you choose to take clients
from for their rules and regulations regarding telenutrition services.

“Cancer Survivorship and Energy Balance:  Going Beyond Obesity”

Suzanne Dixon

Lee Jones


---  The percentage rate of cancer survivors has increased in recent years.

---  Improved fitness levels can improve survivorship further

---   Your fitness levels decrease by 10%  every decade normally

--- Fitness levels decrease by 10% following 12 weeks of chemo in patient

--- Mice studies have shown that when combining exercise with chemo treatments you have a marked decrease in the rate of tumor progression.  


“Myths and Mysteries: Dietary Intake and Diabetes”

Amy Campbell

Osama Hamdy


--- There is no standard Diabetes Diet!!

--- RD’s should individualize diabetic diet therapy

---  High protein and low carb diets for the first two years  is recommended (unless patient also has renal disease)

--- Higher protein diets lower blood glucose lab values, improve cardiovascular health and any change in GFR is not significant.  

--- Change in GFR with diabetic patients is more related to sodium intake than protein.